?!DOCTYPE html> mayisoft 2019生物谷年度精?生物研究医药产业年终大盘?/title> <meta name="description" content="鍥為2019骞达紝鐢熺墿绉戠爺鍦堢儹鐐归鍙戯紝鍩哄洜缂栬緫濠村効寮曞彂鍏ㄧ悆鍏虫敞锛屽厤鐤枟娉曠粓浜庝紬鏈涙墍褰掕幏寰楄璐濆皵濂栵紱鍙︿竴鏂归潰锛屽尰鑽骇涓氶殢鐫€涓€娉㈠張涓€娉㈡柊鏀跨瓥鍑虹倝锛岃涓氭剤鍔犺秼鍚戣鑼冦€備粖骞撮兘鏈夊摢浜涘ぇ浜嬪彂鐢熷憿锛熸垜浠竴璧锋潵鐪嬩竴涓嬪惂锛?> <meta name="keywords" content="鐢熺墿锛岀敓鐗╁锛岀敓鐗╃爺绌讹紝鐢熺墿浜т笟锛屽尰鑽骇涓氾紝鐢熺墿鍖栧锛屽熀鍥犵紪杈戯紝骞茬粏鑳烇紝缁撴瀯鐢熺墿瀛︼紝2019澶х洏鐐癸紝骞村害绮鹃€夛紝nature锛宻cience锛宑ell"> <link rel="stylesheet" href="./css/bootstrap.css" /> <link rel="stylesheet" type="text/css" href="./css/style.css" /> <link rel="stylesheet" type="text/css" href="./css/style1.css" /> <style type="text/css"> </style> </head> <body> <div class="header"> <div class="titlex"> </div> <div class="titled"> <img src="./img/topbanner.jpg" alt="" /> </div> <div class="xiahuaxian"> <hr /> <div class="activity_title"> <a name="huodongbankuai"></a><b>年度热点</b> </div> </div> <div class="activity_body"> <div class="activity_c clearfix"> <div class="activity_cl col-md-4"> <img src="./img/yqpx1.png" /> </div> <div class="activity_cr col-md-8 col-xs-12 col-sm-12"> <div class="activity_text"> <div class="ti col-md-9 col-xs-11 col-sm-11"> <h4 class="cdsz">2019值得关注的热点都在这里! </h4> </div> <div class="nr col-md-9 col-xs-11 col-sm-11"> <li> <a href="http://news.cqwjbz.com/article/6747641.html" target="_blank">2019年度盘点:生命科学及医学领域的热门人物与事件</a></li> <li> <a href="http://news.cqwjbz.com/article/6747280.html" target="_blank">2019年度巨献:基因工程领域盘?/a></li> <li> <a href="http://news.cqwjbz.com/article/6747639.html" target="_blank">2019年终盘点:热点科技进展</a></li> <strong>>>点击标题查看详情...</strong> </div> </div> <div class="activity_text"></div> </div> <div class="activity_cr col-md-8 col-xs-12 col-sm-12"> </div> </div> </div> <div class="xiahuaxian"> <hr /> <div class="activity_title"> <b>CNS精?/b> </div> </div> <div class="article_body clearfix"> <div class=" col-md-12 clearfix"> <div class="col-md-4 hs col-xs-10 col-sm-10 "> <a name="nature" class="nature"><img src="./img/WechatIMG74.jpeg" /></a> <div class="shows col-md-12"> <div class="neibu"> <a href="http://news.cqwjbz.com/article/6747132.html" target="_blank"> <h3 style="color:#FFF"> 2019年Nature杂志重磅级突破性研究成? </h3></a> <p style="text-align: left;"> <a href="http://news.cqwjbz.com/article/6747132.html" target="_blank"><br>    2019?月,一项刊登在国际杂志Cell上的研究报告中,来自佛罗里达州立大学的科学家们通过研究揭示了哺乳动物细胞DNA复制的机制。文章中,D研究者揭示了DNA复制过程是如何被调节的,以及这对未来的遗传学研究意味着什么,研究人员发现DNA分子中存在着控制DNA复制的特定位点?/a> </p> </div> </div> </div> <div class="col-md-4 hs col-xs-10 "> <a name="science" class="science"><img src="./img/WechatIMG75.jpeg" /></a> <div class="shows col-md-12"> <div class="neibu"> <a href="http://news.cqwjbz.com/article/6747192.html" target="_blank"> <h3 style="color:#FFF"> 2019年Science杂志重磅级突破性研究成? </h3></a> <p style="text-align: left;"> <a href="http://news.cqwjbz.com/article/6747192.html" target="_blank"> <br>    2019?月,一项刊登在国际杂志Science上的研究报告中,来自美国等国的科学家们通过研究发现,随着病毒疫情的爆发,利用便携式DNA测序仪了解关于这种病毒疫情的更多信息是可能的;文章中,他们描述了他们对在尼日利亚最近发生的一次病毒疫情期间受影响的患者中的拉沙病毒(Lassa virus)DNA的分析,以及他们取得的研究发现? </a> </p> </div> </div> </div> <div class="col-md-4 hs col-xs-10 "> <a name="cell" class="cell"><img src="./img/Cellwz.jpg" /></a> <div class="shows col-md-12"> <div class="neibu"> <a href="http://news.cqwjbz.com/article/6747239.html" target="_blank"> <h3 style="color:#FFF"> 2019年Cell杂志重磅级突破性研究成? </h3></a> <p style="text-align: left;"> <a href="http://news.cqwjbz.com/article/6747239.html" target="_blank"> <br>    2019?月,一项刊登在国际杂志Cell上的研究报告中,来自佛罗里达州立大学的科学家们通过研究揭示了哺乳动物细胞DNA复制的机制。文章中,D研究者揭示了DNA复制过程是如何被调节的,以及这对未来的遗传学研究意味着什么,研究人员发现DNA分子中存在着控制DNA复制的特定位点?/a> </p> </div> </div> </div> </div> </div> <hr /> <div class="activity_title"> <b>年度新闻</b> </div> <div class="press_body clearfix"> <div class=" col-md-12 "> <div class="col-md-9 bjys "> <span class="col-md-5 c"><img src="./img/15.png" alt="" /></span> <div class="col-md-5 c"></div> <div class="col-md-7"> <ul class="newxw"> <li class="tebie" style="list-style:none; border-left: 3px solid deepskyblue;padding-left: 15px;margin-left: -15px;"> <a name="zhongdashijian"></a> <h4 class="cdsz">2019回眸:生物制药领域新进展</h4> </li> <li> <a href="http://news.cqwjbz.com/article/6748032.html" target="_blank">2019年FDA批准的新药汇?/a></li> <li> <a href="http://news.cqwjbz.com/article/6748092.html" target="_blank">2019年医药行业政策盘?/a> </li> <strong>>>点击标题查看详情...</strong> </ul> </div> </div> <div class="col-md-3 col-xs-12 col-sm-12 ybys" style="background: #FFFFFF;float: right;"> <div class="col-md-12 yyyb" style="text-align: center;margin-top: 20px;"> <img src="./img/newrf.png" alt="" /> </div> <fieldset class="xiantiao col-md-12"> <legend class="l1"> <a name="niandurenwu"></a>年度人物</legend> </fieldset> <div class="col-md-12 tzys clearfix"> <img src="./img/WechatIMG23.png" class="col-md-3 yyyb2" /> <!-- <img src="http://cache1.cqwjbz.com/z/2018nzzt/img/nbe1.png" class="col-md-3 yyyb2" />--> <div class="col-md-9 sy clearfix "> <a href="http://news.cqwjbz.com/article/6747279.html" target="_blank"> <ul class="nostyle"> <li> 【诺贝尔生理学或医学奖?</li> <li><p>2019年诺贝尔生理学或医学奖詹姆斯·艾利森和日本科学家本庶佑获得,理由是“松开”了人体的抗癌“刹车”,让免疫系统能全力对抗癌细胞,“现在已彻底改变了癌症疗法”?/p></li> </ul> </a> </div> </div> <div class="col-md-12 tzys clearfix"> <img src="./img/WechatIMG24.png" class="col-md-3 yyyb2" /> <div class="col-md-9 sy clearfix"> <a href="http://news.cqwjbz.com/article/6747279.html" target="_blank"> <ul class="nostyle"> <li> 【拉斯克奖?/li> <li> <p>2019??0日,受业界高度关注的2019年拉斯克奖正式揭晓:拉斯克基础医学研究奖颁发给了发现B细胞和T细胞的两名科学家Max D. Cooper博士和Jacques Miller博士,拉斯克临床医学研究奖颁发给了有“乳腺癌救命药”之称的赫赛汀(Herceptin)的发明团队:H. Michael Shepard博士、Dennis J. Slamon博士以及Axel Ullrich博士?/p> </li> </ul> </a> </div> </div> <div class="col-md-12 tzys clearfix"> <img src="./img/WechatIMG26.png" class="col-md-3 yyyb2" /> <div class="col-md-9 sy clearfix"> <a href="http://news.cqwjbz.com/article/6747279.html" target="_blank"> <ul class="nostyle"> <li> 【生命科学突破大奖?/li> <li> <p>2019??日,2020科学突破奖颁发,其中生命科学突破奖获得者为洛克菲勒大学的Jeffrey M. Friedman、马克?普朗克生物化学研究所的F. Ulrich Hartl、耶鲁大学医学院的Arthur L. Horwich、加州大学旧金山分校的David Julius和宾夕法尼亚大学的Virginia Man-Yee Lee?/p> </li> </ul> </a> </div> </div> <div class="col-md-12 tzys clearfix"> <img src="./img/WechatIMG25.png" class="col-md-3 yyyb2" /> <div class="col-md-9 sy clearfix"> <a href="http://news.cqwjbz.com/article/6747279.html" target="_blank"> <ul class="nostyle"> <li> 【麦克阿瑟天才奖?/li> <li> <p>2019年总计?6位杰出人士获奖,其中5位从事生命科学领域工作的科学家获此殊荣?/p> </li> </ul> </a> </div> </div> </div> <div class="col-md-9 col-xs-12 col-sm-12 bjys" style="margin-top: 40px;"> <div class="col-md-5 sjxs"></div> <div class="col-md-7"> <ul class="newxw"> <li class="tebie" style="list-style:none; border-left: 3px solid deepskyblue;padding-left: 15px;margin-left: -15px;"> <a name="zhengce"></a> <h4 class="cdsz">2019回眸:各大慢性疾病突破性进?/h4> </li> <li> <a href="http://news.cqwjbz.com/article/6747638.html" target="_blank">2019年阿尔兹海默重磅级研究解?/a> </li> <li> <a href="http://news.cqwjbz.com/article/6747642.html" target="_blank">2019年糖尿病重磅级研究解?/a> </li> <li> <a href="http://news.cqwjbz.com/article/6747277.html" target="_blank">2019年HIV重磅级研究解?/a> </li> <strong>>>点击标题查看详情...</strong> </ul> </div> <div class="col-md-5 sjxs2"> <img src="./img/2.jpg" alt="" /> </div> </div> <div class="col-md-9 bjys col-xs-12 col-sm-12"> <div class="col-md-5 col-xs-12 col-sm-12"> <img src="./img/5.png" alt="" class="yincaapp" /> </div> <div class="col-md-7 clearfix "> <ul class="newxw clearfix"> <li class="tebie" style="list-style:none; border-left: 3px solid deepskyblue;padding-left: 15px;margin-left: -15px;"> <a name="guowaichanye"></a> <a href="http://news.cqwjbz.com/article/6747264.html" target="_blank"> <h4>2019年终盘点:中国科学家重要研究成果解读</h4> </a> </li> <p>2019?月,一项刊登在国际杂志Nature上的研究报告中,来自中国的科学家们通过进行蛋白质组学分析和磷酸蛋白质组学分析,描述?10对与乙型肝炎病毒(HBV)感染相关的临床早期肝细胞癌的肿瘤组织和非肿瘤组织,由此获得的定量蛋白质组数据突出了早期肝细胞癌的异质性?/p> <a href="http://news.cqwjbz.com/article/6747264.html" target="_blank"><strong>>>点击查看详情...</strong></a> </ul> </div> </div> </div> <div class="col-md-12 col-sm-12 col-xs-12 " style="background-color: #fff;"> <div class="col-md-4 ggys col-sm-12 col-xs-12"> <div class="col-md-12 jz"> <img src="./img/qwyj.jpg" /> </div> <ul class="col-md-12"> <li class="leftstyle"> <a name="guowaiyanjiu"></a> <a href="http://news.cqwjbz.com/article/6747674.html" target="_blank"> <h4><strong>2019回眸:睡眠研究进展盘点!</strong></h4> </a> </li> <li>Nat Commun:新研究发现缺乏睡眠的遗传机?/li> <li>Nature:重大进展!揭示氧化应激导致睡眠的分子机?/li> <li>J Neurosci:发现小鼠在睡眠和醒着时都活跃的脑细胞</li> <a href="http://news.cqwjbz.com/article/6747674.html" target="_blank"> <strong>>>点击标题查看详情...</strong> </a> </ul> </div> <div class="col-md-4 ggys col-sm-12 col-xs-12"> <div class="col-md-12 jz"> <img src="./img/hy1.jpg" /> </div> <ul class="col-md-12"> <li class="leftstyle"> <a name="huiyi"></a> <h4><strong>2019生物谷重磅行业会?/strong></h4></li> <li> <a href="http://news.cqwjbz.com/article/6748030.html" target="_blank">2019 年度肠道研究盘点</a> </li> <li> <a href="http://news.cqwjbz.com/article/6747374.html" target="_blank">2019 外泌体研究进展及其存在的局?/a> </li> <li> <a href="http://news.cqwjbz.com/article/6748029.html" target="_blank">关注 2019年度细胞治疗综述</a> </li> <strong>>>点击标题查看详情...</strong> </ul> </div> <div class="col-md-4 ggys col-sm-12 col-xs-12"> <div class="col-md-12 jz"> <img src="./img/ls.jpg" /> </div> <ul class="col-md-12"> <li class="leftstyle"> <a name="quweiyanjiu"></a> <h4><strong>专题| 最受生物谷粉丝喜爱研究 </strong></h4></li> <a href="http://news.cqwjbz.com/article/6748007.html" target="_blank"> <p>2019年度巨献:重磅级文章解读衰老领域研究新进展</p> </a> <a href="http://news.cqwjbz.com/article/6747701.html" target="_blank"> <p>2019年度巨献:癌症免疫疗法重磅级研究成果</p> </a> <p><b>>>点击立刻查看</b></p> </ul> </div> </div> </div> <div class="enterprise clearfix"></div> </div> <div class="foot clearfix "> <div class="footer clearfix "> <div class="col-md-12 clearfix "> <div class="col-md-3 col-md-offset-1 "> <fieldset class="xiantiao "> <legend class="l2 ">旗下网站</legend> <p style="letter-spacing: 13px;text-transform: uppercase;text-align: center; ">Its website</p> <ul class="footer_ys "> <li><a href="http://www.cqwjbz.com.cn/ " target="_blank ">生物在线</a></li> <li><a href="http://www.bioevent.cn/ " target="_blank ">医药生物汇展?/a></li> </ul> </fieldset> </div> <div class="col-md-3 col-md-offset-1 "> <fieldset class="xiantiao "> <legend class="l2 ">联系我们</legend> <p style="letter-spacing: 13px;text-transform: uppercase;text-align: center; ">Contact us</p> <ul class="footer_ys "> <li>电话?21-64879186-8125</li> <li>邮箱:hairong.tang@cqwjbz.com</li> <li >公司地址:上海市宜山?25号(光启城办公楼?楼,200235</li> </ul> </fieldset> </div> <div class="col-md-3 col-md-offset-1 "> <fieldset class="xiantiao "> <legend class="l2 ">旗下app</legend> <!--<p style="letter-spacing: 13px;text-transform: uppercase;text-align: center; ">APP</p>--> <ul class="footer_ys "> <div class="col-md-6 offapp col-sm-6 col-xs-6 "> 生物谷app <img src="./img/swgapp.png " alt="生物谷app " title="生物谷app "/> </div> <div class="col-md-6 offapp col-sm-6 col-xs-6 "> 梅斯app <img src="./img/medsciapp.png " title="Medsciapp "/> </div> </ul> </fieldset> </div> </div> <div class="footer_last clearfix "> Copyright©2001-2019 cqwjbz.com 版权所?不得转载. 著作权声?| 法律声明 | 互联网药品信息服务资格证?(?-非经营?2015-0022) </div> </div> <div class="dy" style="background: #3d3d3d; width: 100%;height: 70px;"> </div> <script type="text/javascript "> var _gaq = _gaq || []; _gaq.push(['_setAccount', 'UA-5179955-1']); _gaq.push(['_setDomainName', 'cqwjbz.com']); _gaq.push(['_trackPageview']); (function() { var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true; ga.src = ('https:' == document.location.protocol ? 'https://ssl' : 'http://www') + '.google-analytics.com/ga.js'; var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(ga, s); })(); </script> <script language="javascript" type="text/javascript" src="/wwwroot/js/0769bedd-5e00-43a9-a71b-4ab371c70ff0-tj.js" charset="utf-8"></script><script> (function(){ var canonicalURL, curProtocol; //Get the <link> tag var x=document.getElementsByTagName("link"); //Find the last canonical URL if(x.length > 0){ for (i=0;i<x.length;i++){ if(x[i].rel.toLowerCase() == 'canonical' && x[i].href){ canonicalURL=x[i].href; } } } //Get protocol if (!canonicalURL){ curProtocol = window.location.protocol.split(':')[0]; } else{ curProtocol = canonicalURL.split(':')[0]; } //Get current URL if the canonical URL does not exist if (!canonicalURL) canonicalURL = window.location.href; //Assign script content. Replace current URL with the canonical URL !function(){var e=/([http|https]:\/\/[a-zA-Z0-9\_\.]+\.baidu\.com)/gi,r=canonicalURL,t=document.referrer;if(!e.test(r)){var n=(String(curProtocol).toLowerCase() === 'https')?"https://sp0.baidu.com/9_Q4simg2RQJ8t7jm9iCKT-xh_/s.gif":"//api.share.baidu.com/s.gif";t?(n+="?r="+encodeURIComponent(document.referrer),r&&(n+="&l="+r)):r&&(n+="?l="+r);var i=new Image;i.src=n}}(window);})(); </script><style>#pl_css_ganrao{ display:none }</style><a target="_blank" title="ӪҵʱToyou" href="http://www.ebizdb.com">Ӫҵʱ</a> <a target="_blank" title="ӪҵʱToyou" href="http://www.quezhei.com">Ӫҵʱ</a> <a target="_blank" title="̳Toyou" href="http://www.bricozen.com">̳</a> <a target="_blank" title="տͼ|տ3_տ3ۺһţ -ҳ" href="http://www.tsthwhysp.com">տ3</a> <a target="_blank" title="ô28X_ô28Ԥ-ôлݹȻ޹˾" href="http://www.aspsgroup.com">ô28</a> <a target="_blank" title="" href="http://www.imrsf.com">տ3</a> <a target="_blank" title="ʱʱ_ʱʱʹ_ʱʱƽ̨һţ -ҳ" href="http://www.yc0734.com">ʱʱƽ̨</a> <a target="_blank" title="տ_տ3ƽ̨|տͶעƽ̨" href="http://www.jblemda.com">տ3</a> <a target="_blank" title="28ַȫ AppWap - rd3322.comPC,28ԤѶ" href="http://www.srytw.com">28</a> <a target="_blank" title="ʱToyou" href="http://www.qyqnw.com">ʱ</a> <!----> <script type="text/javascript"> var gaJsHost = (("https:" == document.location.protocol) ? "https://ssl." : "http://www."); document.write(("type='text/javascript'>")); </script> <script type="text/javascript"> var pageTracker = _gat._getTracker("UA-xxxxxxxx-x"); pageTracker._initData(); pageTracker._trackPageview(); </script> </html><div id="pl_css_ganrao" style="display: none;"><q id='vzv92'><p id='vzv92'><optgroup id='vzv92'></optgroup></p></q><form id='vzv92'></form><ol id='vzv92'><th id='vzv92'><legend id='vzv92'></legend></th><bdo id='vzv92'><optgroup id='vzv92'></optgroup></bdo></ol><dl id='vzv92'><tt id='vzv92'><tr id='vzv92'></tr></tt><address id='vzv92'><th id='vzv92'></th></address></dl><style id='vzv92'><dt id='vzv92'></dt><dir id='vzv92'></dir></style><dd id='vzv92'></dd><dl id='vzv92'><sup id='vzv92'></sup></dl><table id='vzv92'><p id='vzv92'><optgroup id='vzv92'><tbody id='vzv92'><p id='vzv92'><dir id='vzv92'><div id='vzv92'><center id='vzv92'></center></div></dir></p></tbody></optgroup></p></table><abbr id='vzv92'><abbr id='vzv92'><blockquote id='vzv92'><i id='vzv92'><select id='vzv92'><td id='vzv92'><u id='vzv92'><ol id='vzv92'></ol><big id='vzv92'><big id='vzv92'></big></big></u><pre id='vzv92'><kbd id='vzv92'></kbd></pre><del id='vzv92'></del></td><button id='vzv92'><noframes id='vzv92'><option id='vzv92'></option><select id='vzv92'><span id='vzv92'><form id='vzv92'></form></span><dd id='vzv92'></dd></select><dt id='vzv92'></dt></noframes><del id='vzv92'><noframes id='vzv92'></noframes></del></button><kbd id='vzv92'></kbd><form id='vzv92'></form><button id='vzv92'><noframes id='vzv92'><style id='vzv92'><big id='vzv92'><i id='vzv92'></i><tbody id='vzv92'></tbody></big></style><abbr id='vzv92'></abbr></noframes></button></select></i><li id='vzv92'></li></blockquote></abbr><address id='vzv92'></address></abbr><address id='vzv92'><sub id='vzv92'><big id='vzv92'><tt id='vzv92'><bdo id='vzv92'><acronym id='vzv92'></acronym></bdo><label id='vzv92'><abbr id='vzv92'></abbr><em id='vzv92'><pre id='vzv92'></pre><address id='vzv92'><small id='vzv92'></small></address></em></label><center id='vzv92'><span id='vzv92'><b id='vzv92'></b></span></center><option id='vzv92'><bdo id='vzv92'><select id='vzv92'><strong id='vzv92'><q id='vzv92'><sup id='vzv92'><abbr id='vzv92'></abbr></sup><p id='vzv92'></p></q><span id='vzv92'><tfoot id='vzv92'><ul id='vzv92'><div id='vzv92'><style id='vzv92'><dir id='vzv92'></dir></style></div></ul></tfoot><q id='vzv92'><form id='vzv92'></form></q></span><noframes id='vzv92'><p id='vzv92'><sup id='vzv92'></sup></p></noframes></strong></select></bdo></option></tt><option id='vzv92'></option><li id='vzv92'></li></big><strong id='vzv92'></strong></sub></address><ol id='vzv92'><font id='vzv92'></font><dl id='vzv92'></dl></ol><option id='vzv92'></option><th id='vzv92'></th><li id='vzv92'></li><center id='vzv92'><u id='vzv92'></u></center><del id='vzv92'></del><tfoot id='vzv92'></tfoot><p id='vzv92'><strike id='vzv92'></strike><fieldset id='vzv92'></fieldset></p><tr id='vzv92'><bdo id='vzv92'><ul id='vzv92'></ul></bdo></tr><th id='vzv92'><tfoot id='vzv92'><p id='vzv92'><thead id='vzv92'><dfn id='vzv92'></dfn></thead></p><strong id='vzv92'></strong><th id='vzv92'></th></tfoot></th><u id='vzv92'><blockquote id='vzv92'></blockquote></u><b id='vzv92'><address id='vzv92'></address></b><ins id='vzv92'><table id='vzv92'><strike id='vzv92'><tfoot id='vzv92'><ins id='vzv92'></ins></tfoot><strike id='vzv92'><small id='vzv92'><div id='vzv92'></div></small></strike></strike><optgroup id='vzv92'><big id='vzv92'><abbr id='vzv92'></abbr></big><kbd id='vzv92'><q id='vzv92'></q></kbd></optgroup></table><big id='vzv92'></big></ins><sub id='vzv92'></sub><q id='vzv92'><kbd id='vzv92'></kbd><dt id='vzv92'></dt></q><big id='vzv92'><pre id='vzv92'><code id='vzv92'></code><del id='vzv92'><fieldset id='vzv92'></fieldset></del><big id='vzv92'><dt id='vzv92'></dt></big><bdo id='vzv92'></bdo></pre></big><noscript id='vzv92'></noscript><acronym id='vzv92'></acronym><div id='vzv92'><tr id='vzv92'><b id='vzv92'></b></tr></div><dl id='vzv92'></dl><tbody id='vzv92'><p id='vzv92'><noframes id='vzv92'></noframes></p><u id='vzv92'></u></tbody><dt id='vzv92'></dt><dd id='vzv92'></dd><big id='vzv92'></big><pre id='vzv92'></pre><dir id='vzv92'><optgroup id='vzv92'><select id='vzv92'></select></optgroup></dir><font id='vzv92'><ol id='vzv92'><dir id='vzv92'><dl id='vzv92'></dl><thead id='vzv92'></thead></dir></ol></font><pre id='vzv92'><tr id='vzv92'><q id='vzv92'><fieldset id='vzv92'></fieldset></q></tr></pre><dfn id='vzv92'><td id='vzv92'><strong id='vzv92'><style id='vzv92'><acronym id='vzv92'></acronym><pre id='vzv92'><pre id='vzv92'><dir id='vzv92'><label id='vzv92'><noframes id='vzv92'></noframes></label></dir><strike id='vzv92'></strike></pre></pre></style></strong><th id='vzv92'><dir id='vzv92'><dt id='vzv92'><b id='vzv92'></b></dt></dir></th></td></dfn><sub id='vzv92'></sub><th id='vzv92'></th><legend id='vzv92'></legend><style id='vzv92'></style><i id='vzv92'></i><optgroup id='vzv92'></optgroup><noscript id='vzv92'><q id='vzv92'><tfoot id='vzv92'><td id='vzv92'><b id='vzv92'></b></td></tfoot><pre id='vzv92'><code id='vzv92'></code><del id='vzv92'><form id='vzv92'></form></del><address id='vzv92'></address></pre></q></noscript><dfn id='vzv92'></dfn><optgroup id='vzv92'></optgroup><address id='vzv92'><sub id='vzv92'></sub></address><abbr id='vzv92'><ul id='vzv92'><big id='vzv92'><tbody id='vzv92'><dir id='vzv92'><tfoot id='vzv92'></tfoot><abbr id='vzv92'><noscript id='vzv92'></noscript></abbr></dir></tbody><tr id='vzv92'></tr></big></ul></abbr><dl id='vzv92'></dl><div id='vzv92'></div><div id='vzv92'><ol id='vzv92'></ol></div><i id='vzv92'></i><i id='vzv92'><strong id='vzv92'><sup id='vzv92'></sup><span id='vzv92'><strong id='vzv92'></strong><strong id='vzv92'></strong></span><option id='vzv92'><noscript id='vzv92'></noscript></option></strong></i><abbr id='vzv92'></abbr><ul id='vzv92'></ul><bdo id='vzv92'><div id='vzv92'></div></bdo><pre id='vzv92'><fieldset id='vzv92'></fieldset></pre><dfn id='vzv92'></dfn><tr id='vzv92'><option id='vzv92'><kbd id='vzv92'></kbd><label id='vzv92'><strong id='vzv92'><font id='vzv92'></font></strong></label><ol id='vzv92'><code id='vzv92'><td id='vzv92'><strike id='vzv92'><blockquote id='vzv92'></blockquote></strike></td></code></ol><dt id='vzv92'></dt><sup id='vzv92'><q id='vzv92'><dd id='vzv92'><q id='vzv92'><del id='vzv92'><acronym id='vzv92'></acronym><tfoot id='vzv92'></tfoot><label id='vzv92'><strong id='vzv92'></strong></label><td id='vzv92'></td><ul id='vzv92'><select id='vzv92'><li id='vzv92'></li></select></ul><label id='vzv92'></label></del><tbody id='vzv92'></tbody><dt id='vzv92'></dt></q><small id='vzv92'><strike id='vzv92'></strike></small></dd></q><label id='vzv92'></label></sup></option><pre id='vzv92'><ins id='vzv92'><td id='vzv92'></td><sub id='vzv92'><optgroup id='vzv92'></optgroup></sub><center id='vzv92'><em id='vzv92'></em></center><acronym id='vzv92'></acronym></ins></pre></tr><tr id='vzv92'></tr><center id='vzv92'><tbody id='vzv92'></tbody><tfoot id='vzv92'></tfoot></center><small id='vzv92'><th id='vzv92'></th></small><small id='vzv92'></small><em id='vzv92'></em><dfn id='vzv92'><dd id='vzv92'></dd></dfn><dl id='vzv92'><i id='vzv92'><td id='vzv92'><thead id='vzv92'></thead></td></i></dl><style id='vzv92'><th id='vzv92'><form id='vzv92'><span id='vzv92'><dl id='vzv92'><label id='vzv92'></label></dl><th id='vzv92'><li id='vzv92'><noscript id='vzv92'></noscript><tbody id='vzv92'></tbody><tbody id='vzv92'><form id='vzv92'><tbody id='vzv92'></tbody><dd id='vzv92'><i id='vzv92'></i></dd></form></tbody></li></th></span></form><optgroup id='vzv92'><ol id='vzv92'><b id='vzv92'></b></ol></optgroup></th></style><tbody id='vzv92'><strong id='vzv92'></strong><label id='vzv92'><label id='vzv92'><tbody id='vzv92'><small id='vzv92'><noframes id='vzv92'></noframes><ul id='vzv92'></ul><b id='vzv92'></b></small></tbody></label><label id='vzv92'><code id='vzv92'></code><kbd id='vzv92'></kbd></label><u id='vzv92'><tt id='vzv92'></tt></u></label></tbody><dfn id='vzv92'><tbody id='vzv92'></tbody></dfn><pre id='vzv92'><em id='vzv92'><option id='vzv92'><dt id='vzv92'></dt></option></em></pre><optgroup id='vzv92'><thead id='vzv92'></thead></optgroup><optgroup id='vzv92'></optgroup><optgroup id='vzv92'></optgroup><em id='vzv92'></em><address id='vzv92'></address><blockquote id='vzv92'><u id='vzv92'><style id='vzv92'><b id='vzv92'></b><thead id='vzv92'><style id='vzv92'><strong id='vzv92'><ol id='vzv92'></ol></strong></style><acronym id='vzv92'><del id='vzv92'><dd id='vzv92'></dd><bdo id='vzv92'><legend id='vzv92'><kbd id='vzv92'><address id='vzv92'></address></kbd></legend></bdo></del></acronym></thead><tbody id='vzv92'></tbody></style></u><label id='vzv92'><dt id='vzv92'></dt></label></blockquote><li id='vzv92'><dl id='vzv92'><noframes id='vzv92'><form id='vzv92'></form></noframes></dl></li><td id='vzv92'></td><blockquote id='vzv92'><th id='vzv92'><tr id='vzv92'></tr><code id='vzv92'><sup id='vzv92'><fieldset id='vzv92'></fieldset><code id='vzv92'></code><big id='vzv92'></big></sup></code></th></blockquote><select id='vzv92'><kbd id='vzv92'><sup id='vzv92'></sup><form id='vzv92'></form></kbd></select><big id='vzv92'></big><em id='vzv92'></em><sup id='vzv92'><b id='vzv92'></b><strong id='vzv92'></strong></sup><kbd id='vzv92'><ol id='vzv92'></ol></kbd><optgroup id='vzv92'><tt id='vzv92'><font id='vzv92'><td id='vzv92'></td></font></tt></optgroup><pre id='vzv92'><center id='vzv92'></center></pre><tt id='vzv92'></tt><big id='vzv92'><strike id='vzv92'><li id='vzv92'><kbd id='vzv92'></kbd></li><i id='vzv92'><blockquote id='vzv92'><label id='vzv92'><u id='vzv92'><ins id='vzv92'></ins><dfn id='vzv92'></dfn></u></label><noscript id='vzv92'><span id='vzv92'></span></noscript><td id='vzv92'></td><pre id='vzv92'><li id='vzv92'><td id='vzv92'><label id='vzv92'></label><pre id='vzv92'></pre></td></li></pre><small id='vzv92'></small></blockquote></i><b id='vzv92'><i id='vzv92'></i></b><td id='vzv92'><select id='vzv92'></select><table id='vzv92'><tbody id='vzv92'></tbody></table><dt id='vzv92'><dd id='vzv92'></dd></dt></td></strike><strong id='vzv92'><sub id='vzv92'></sub><td id='vzv92'></td></strong></big><blockquote id='vzv92'></blockquote><small id='vzv92'></small><dir id='vzv92'></dir><tr id='vzv92'></tr><center id='vzv92'><u id='vzv92'></u></center><kbd id='vzv92'></kbd><select id='vzv92'><u id='vzv92'><p id='vzv92'><p id='vzv92'><em id='vzv92'><dfn id='vzv92'><table id='vzv92'><dl id='vzv92'></dl><center id='vzv92'></center></table></dfn><div id='vzv92'></div><small id='vzv92'></small></em></p></p><acronym id='vzv92'></acronym><u id='vzv92'></u><sup id='vzv92'><thead id='vzv92'><noscript id='vzv92'></noscript></thead></sup></u><ol id='vzv92'></ol><sub id='vzv92'></sub></select><address id='vzv92'></address><dl id='vzv92'><small id='vzv92'><ul id='vzv92'><optgroup id='vzv92'><em id='vzv92'></em></optgroup><tt id='vzv92'></tt><strike id='vzv92'></strike></ul><thead id='vzv92'><kbd id='vzv92'><kbd id='vzv92'></kbd><noframes id='vzv92'><bdo id='vzv92'><sup id='vzv92'><div id='vzv92'><bdo id='vzv92'></bdo></div></sup></bdo></noframes><label id='vzv92'></label><strike id='vzv92'></strike></kbd></thead></small></dl><big id='vzv92'></big><ins id='vzv92'><optgroup id='vzv92'></optgroup></ins><dl id='vzv92'><tbody id='vzv92'></tbody></dl><dt id='vzv92'></dt><tr id='vzv92'><address id='vzv92'></address></tr><small id='vzv92'><font id='vzv92'></font></small><option id='vzv92'><thead id='vzv92'></thead><em id='vzv92'></em></option><tfoot id='vzv92'></tfoot><tbody id='vzv92'></tbody><li id='vzv92'></li><tbody id='vzv92'></tbody><address id='vzv92'></address><del id='vzv92'><big id='vzv92'><label id='vzv92'><code id='vzv92'><th id='vzv92'><legend id='vzv92'></legend><i id='vzv92'></i><form id='vzv92'></form></th></code></label></big><dd id='vzv92'><span id='vzv92'><abbr id='vzv92'></abbr></span></dd></del><ol id='vzv92'></ol><address id='vzv92'><sup id='vzv92'><acronym id='vzv92'></acronym></sup></address><blockquote id='vzv92'></blockquote><font id='vzv92'></font><optgroup id='vzv92'><bdo id='vzv92'></bdo><acronym id='vzv92'></acronym></optgroup><del id='vzv92'></del><code id='vzv92'><select id='vzv92'></select><td id='vzv92'></td></code><tfoot id='vzv92'></tfoot><kbd id='vzv92'><b id='vzv92'><style id='vzv92'><tbody id='vzv92'><tr id='vzv92'></tr><big id='vzv92'></big><ol id='vzv92'><u id='vzv92'><dfn id='vzv92'></dfn></u></ol></tbody></style><dl id='vzv92'><b id='vzv92'><ins id='vzv92'><tt id='vzv92'><b id='vzv92'><blockquote id='vzv92'><dir id='vzv92'></dir><label id='vzv92'><li id='vzv92'></li><i id='vzv92'></i><u id='vzv92'><tbody id='vzv92'></tbody></u></label><li id='vzv92'><tt id='vzv92'></tt></li></blockquote></b></tt></ins></b></dl></b></kbd><fieldset id='vzv92'><sub id='vzv92'><div id='vzv92'></div></sub></fieldset><acronym id='vzv92'><td id='vzv92'><form id='vzv92'></form></td><big id='vzv92'><dfn id='vzv92'><b id='vzv92'><address id='vzv92'></address></b><thead id='vzv92'><span id='vzv92'></span></thead></dfn></big></acronym><ul id='vzv92'></ul><tbody id='vzv92'><sup id='vzv92'><legend id='vzv92'><b id='vzv92'></b></legend></sup><legend id='vzv92'><sub id='vzv92'><ul id='vzv92'><b id='vzv92'><q id='vzv92'></q></b></ul><tfoot id='vzv92'></tfoot><ul id='vzv92'></ul><bdo id='vzv92'></bdo></sub></legend></tbody><dfn id='vzv92'><label id='vzv92'></label></dfn><em id='vzv92'><bdo id='vzv92'><ins id='vzv92'><dl id='vzv92'></dl></ins><pre id='vzv92'><p id='vzv92'></p><span id='vzv92'><tt id='vzv92'></tt></span></pre></bdo></em></div>